Conolidine’s analgesic results stem from its interaction with non-opioid pain pathways. In contrast to opioids, which bind to µ-opioid receptors within the central nervous process, conolidine modulates alternate molecular targets. A Science Advancements review located that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. https://isconolidinearealpainreli10741.blogerus.com/60302987/not-known-factual-statements-about-alternative-natural-pain-relief-to-replace-traditional-painkillers