Exploration into conolidine has brought about discovery of the opioid receptor in the body identified as ACKR3/CXCR7. ACKR3 seems to be one of the most desired goal for conolidine, which also disregards the other 4 classical opioid receptors(3). There exists interest in employing conolidine being a pain-reliever according to https://shanetchjm.blogzag.com/81689228/not-known-factual-statements-about-alternative-natural-pain-relief-to-replace-traditional-painkillers