At 3 times submit-MPTP, we identified sizeable microglial activation and up-regulation of CB2 cannabinoid receptors within the ventral midbrain. Treatment method with WIN or the CB2 receptor agonist JWH015 (four mg/kg, intraperitoneal) decreased MPTP-induced microglial activation, While genetic ablation of CB2 receptors exacerbated MPTP systemic toxicity. On top of that, https://win55.clinic/tin-tuc