Due to the fact oxycodone is metabolized because of the cytochrome P450 program during the liver, its pharmacokinetics may be affected by genetic polymorphisms and drug interactions concerning this system, and also by liver purpose.[46] Some people are rapid metabolizers of oxycodone, while some are sluggish metabolizers, causing polymorphism-dependent alterations https://csgohealth.com/understanding-oxycodone-uses-risks-and-safe-practices/